CPPsite 2.0 is an updated version of database CPPsite, it contains around 1700 unique cell penetrating peptides (CPPs) alongwith their secondary & tertiary structure. This database maintains experimentally validated CPPs (linear & cyclic; modified & non-natural residues) and wide range of cargos (nucleic acids, proteins, nanoparticles, PNA) delivered in cells using these peptides. For previous version of CPPsite click here
Comprehensive Information: This version contains 1855 entries where each entry provides extensive information about a CPP that includes; i) peptide sequence, ii) nature of peptide, iii) chemical modifications, iv) experimental validation techniques, v) structure of peptides and vi) type of cargo delivered.
Searching Facilities: Searching modules allow users to retrieve data from database using various options that includes; i) searching on any field, ii) identical secondary structure, iii) composition/frequency of residues and iv) composition of secondary structure.
Group-wise Data Browsing: Modules under this section allow the users to retrieved data in classified manner. These modules allow user to browse CPPs of different categories that include cyclic, synthetic, nucleic-acid delivering, small peptides.
Similarity Search: It mainatins primary, secondary and tertiary structure of all peptides; peptide structures were either obtained from PDB or predicted using structure prediction methods (PepStrMod and I-TASSER). Web based tools integrated in CPPsite 2.0 allow users to perform similarity based search on sequence, structure or composition.
Mobile Compatible Website: CPPsite 2.0 is built on a responsive template, compatible for desktop, tablet and smart phone. These templates are dynamic that fit content based on screen size of device.